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10% Hydroxyapatite Fluoride-Free

Hydroxyapatite Serum

$60.00 USD

Real Results. No Toxins. No Compromise.

This isn't your typical oral care product, it's a dental-grade oral care serum for remineralization.

Formulated with micro-hydroxyapatite, soothing botanicals, and microbiome-friendly actives, our Hydroxyapatite Serum delivers next-level care to strengthen enamel, reduce sensitivity, and support total-mouth wellness.

Why You’ll Love It

  • Non-Toxic, Dentist-Grade Protection Powered by 10% micro hydroxyapatite, a clinically studied alternative to fluoride that strengthens enamel and whitens teeth, safely.
  • Reduces Tooth Sensitivity Fast
    Our two-particle HAP system targets both surface enamel and deeper tubules to seal and soothe sensitive teeth.
  • Supports a Healthy Oral Microbiome
    With L-Arginine, Xylitol, and Peppermint Oil, this serum helps create a mouth environment where good bacteria thrive, and bad ones don’t.
  • Whitens Naturally
    Gentle, non-abrasive brightening thanks to Aloe, Sodium Bicarbonate, and hydroxyapatite, no bleaching agents or harsh chemicals.
  • Safe for the Whole Family
    Fluoride-free, toxin-free, and safe enough for kids, this is the daily oral care boost your household can trust.

Micro-Hydroxyapatite (10%)

A natural, bio-identical mineral that remineralizes enamel and reduces sensitivity.

  • 5% over 3 microns: remineralizes surface enamel
  • 5% under 3 microns: enters dentin tubules to seal and soothe.

Xylitol

Helps prevent cavities by inhibiting Streptococcus mutans and encouraging saliva production. Supports a balanced oral pH.

L-Arginine

Helps neutralize acidity and promotes beneficial nitrate-reducing bacteria for microbiome health.

Aloe Vera

Soothes gums, reduces inflammation, and may help reduce staining and gingivitis.

Humic & Fulvic Acids

Detoxifying, antimicrobial compounds that help remove toxins, support healing, and reduce inflammation.

  • Humic: “Nature’s Janitor” – attracts and removes bio-waste and heavy metals.
  • Fulvic: Delivers nutrients into cells and supports detoxification.

Peppermint Oil

Naturally antimicrobial and refreshing, supports fresh breath and a healthy mouth.

Sodium Bicarbonate

Balances pH, gently whitens, and supports healthy bacteria.

Alpha Bisabolol

A powerful, plant-based anti-inflammatory (from chamomile) that supports healing and reduces oral irritation.

PURIFIED WATER, SORBITOL, HYDROXYAPATITE, XYLITOL, XANTHAN GUM, POTASSIUM SORBATE, POTASSIUM CHLORIDE, L-ARGININE, ALOE VERA, STEVIA, PEPPERMINT OIL, SODIUM BICARBONATE, HUMIC ACID, FULVIC ACID, ALPHA BISABOLOL

Brush on, let sit, and rinse.

Apply directly to the teeth using a toothbrush or finger. Let sit for 30 minutes to allow the formula to penetrate and remineralize. Rinse gently with water. Use once daily for best results.

The tube and caps are fully recyclable.

Order within the next 23 hours 11 minutes to receive it. Estimated delivery is between Sunday, 21 Jun and Tuesday, 23 Jun.
  • Fluoride-free
  • Glycerin-free
  • Natural micro-hydroxyapatite
  • Remineralizes tooth enamel
  • Sustainably sourced
  • Made in the USA
  • Safe for all ages
  • Trusted by Dentists and B-corp Certified

60 DAY MONEY-BACK GUARANTEE

If you're not happy with your purchase for whatever reason, just contact our customer service team within 60 days and we'll make sure you're happy.

How We Measure Up

Compare our formulation to the competition.

Wellnesse Competitor #1 Competitor #2
Price ✔️ $60 for 1.75 oz ✖️ $125 for 1.36 oz ✖️ $98 for 1.25 oz
Strength ✔️ 10% Active Micro-Hydroxyapatite ✖️ 8.6% Nano-Hydroxyapatite ✖️ 8% Nano-Hydroxyapatite
Quality ✔️ Safe for all ages and daily use ✖️ Nano-hydroxyapatite may pose potential health risks, according to some research. ✖️ Nano-hydroxyapatite may pose potential health risks, according to some research.
Wellnesse hydroxyapatite serum fluoride-free tube on a natural wood slice with green foliage backdrop

Hydroxyapatite Serum

$60.00

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Meet Our NEW Professional-Grade, Remineralizing Serum

Upgrade your oral care routine with our most powerful fluoride-free formula yet.

This daily-use tooth serum features 10% micro hydroxyapatite in two optimized particle sizes to remineralize enamel, reduce sensitivity, and restore your natural whiteness — all while supporting your oral microbiome. It’s like a fluoride varnish… without the fluoride.

Why You’ll Love It

  • Helps relieve sensitivity
  • Strengthens enamel
  • Whitens naturally
  • Neutralizes mouth acidity
  • Promotes healthy bacteria
  • Safe for kids and adults
  • Free from fluoride, SLS, parabens & artificial dyes
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Oral Care Approved by Top Dental Professionals

What Experts Are Saying

  • DR. MEGHAN THOMAS, DMD

    DR. MEGHAN THOMAS, DMD

    "I use Wellnesse toothpaste and recommend it to my patients.

    It contains hydroxyapatite, that helps support tooth enamel to keep teeth strong. Wellnesse toothpaste gets your teeth just as white (if not whiter) than everything else - without all the chemicals. Why would anyone NOT switch?”

  • DR. RYAN PORTER, DDS

    DR. RYAN PORTER, DDS

    "I highly recommend it for all my patients. It's simply much healthier and reparative.

    Wellnesse is amazing! Not only do I use Wellnesse for my personal care, I highly recommend it for all my patients. It's simply much healthier and reparative."

  • CHELSEA PULEO

    CHELSEA PULEO

    "I love their philosophy as well as their clean ingredient list.

    Finding a toothpaste with clean ingredients that actually works has been a challenge for me. When I discovered Wellnesse, I knew it was the right fit for us… I love their philosophy as well as their clean ingredient list!"

4.9
Rated 4.9 out of 5 stars
Based on 14 reviews
Total 5 star reviews: 12 Total 4 star reviews: 2 Total 3 star reviews: 0 Total 2 star reviews: 0 Total 1 star reviews: 0
100%would recommend this product
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14 reviews
  • SE
    Stephanie E.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    1 month ago
    Grateful

    A friend turned me onto the Wellnesse products. i’ve been using the toothpaste for a while and really like it. When they came out with this product, I wanted to try it. At first it looked like it was kind of pricey for what it was. But I read the information on the website and realized that this is micro hydroxyapatite not nano. Big difference! So I’m grateful to find a clean version! No more cavities or hypersensitivity!

  • LM
    LuAnn M.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    3 months ago
    It works!

    I have had sensitive teeth due to grinding over the years and decided to try the serum. I had been using hydroxyapatite toothpaste for a couple weeks already. The serum IS WONDERFUL. I am so grateful it works! No more sensitivity 💓

  • AS
    anthony S.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    3 months ago
    Serum

    High quality works great just started but works great fast shipping

  • K
    Katrina
    I recommend this product
    Rated 5 out of 5 stars
    2 weeks ago
    Amazing

    Dr VerdiVita herbal treatment cured my Parkinson's disease, they also treat Alzheimer's, multiple sclerosis, and other neurological disorders. Message them today to be free from any of your health issues. If you are seeking guidance for your own health concerns you can reach them at: Email: healeroseiwe112@ gmail.com or

    WhatsApp: *****0doc

  • JV
    John V.
    Verified Buyer
    I recommend this product
    Rated 4 out of 5 stars
    3 weeks ago
    Great Tooth serum.

    Works Great. I wish it wasn’t so expensive.

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"I am so grateful to have found this healthy alternative and my whole family is now using it and loving it!! Thank you Wellnesse!"

- Michele K.

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